

A simple explanation of what’s happening in the brain—and why symptoms affect more than movement.
Parkinson's symptoms are not random—they are caused by changes in how the brain sends signals.
Dopamine is a chemical messenger in the brain that helps control:
• Movement
• Mood
• Focus
• Sleep
• Motivation
It allows different parts of the brain to communicate with each other.
In Parkinson’s disease, the brain cells that produce dopamine gradually stop working.As dopamine levels drop, the brain can’t send clear signals to the body.
Because dopamine controls many functions, Parkinson's affects far more than movement. Parkinson’s can affect:
• Movement
• Thinking
• Emotions
• Sleep
• Energy
• Digestion
Why symptoms fluctuateSymptoms can change throughout the day because:
—Dopamine levels rise and fall
—Medication wears off
—The brain responds differently over time
This leads to "on" and "off" periods
It is a brain communication problem.Symptoms reflect how the brain is functioning—not effort, attitude, or mindset.Understanding this is the first step to managing symptoms.
© 2026 TooShaky
Disclaimer: This patient education resource was created by Dawn Howard, Parkinson’s Advocate & Neurological Health Educator, through TooShaky.org, to support individuals newly diagnosed with Parkinson’s disease. Content is informed by lived experience, patient education best practices, and information from established medical, nonprofit, and educational sources. Drafting, editing, and organizational support were assisted by ChatGPT (OpenAI) as a writing and language tool, under the direction and review of the author. Educational content and references are drawn from sources including, but not limited to: Parkinson’s Foundation, The Michael J. Fox Foundation for Parkinson’s Research, American Parkinson Disease Association (APDA), Davis Phinney Foundation, Mayo Clinic, Peer-reviewed medical literature and clinical education resources. This material is provided for informational and educational purposes only and is not intended to replace individualized medical advice, diagnosis, or treatment. Patients should discuss all medical questions and care decisions with their healthcare provider. TooShaky.org does not provide medical care and does not establish a clinician–patient relationship.